Skip Navigation
InitialsDiceBearhttps://github.com/dicebear/dicebearhttps://creativecommons.org/publicdomain/zero/1.0/„Initials” (https://github.com/dicebear/dicebear) by „DiceBear”, licensed under „CC0 1.0” (https://creativecommons.org/publicdomain/zero/1.0/)RO
Posts 3
Comments 197
What gives you hope to keep going?
  • I work in disability support. Some of the kids I am working with have gone over the last year from non speaking to using sign and are making real meaningful progress in their self care skills. They can keep going in the face of difficult times, so my problems don't seem so hard.

    Also, in Australia we have the NDIS, a system for funding disability supports in a socialised manner without restricting what options someone uses too much. While all governmental systems (or any systems with money) are susceptible to grift progress is being made on catching fraudsters and prosecuting them while also closing the loopholes they exploit. The NDIS will be around for a long time to come and will help Australians with disabilities determine their own futures and make them a reality. There are problems with it but honestly it has been a game changer and I think it is a model for the rest of the world to aspire to.

  • Warfarin dose in this study seems very similar in outcomes but does not meet non inferiority. Why?
  • Happily it seems they did do more.

    Follow up study

    They took the same control group and did a second set of experimental participants. They did find a difference between the groups, quite a significant one to be honest.

    Now to see if it replicates, maybe we can aim for a lower INR. It would be ideal to not have quite so much bleed risk but also to not clot.

    Edit: also, I am on warfarin and asparin with a mechanical valve, I was recommended a mechanical valve as it should outlast me and if I had a biovalve it would need replacement in 15 years max at which point it would be mechanical anyway. I'm in my mid thirties so if I have a second major surgery at 50 I will have to repair bone and muscle again and have rehab again, all at a lower likelihood of recovery. Going full mechanical means one surgery, lifelong warfarin, and one set of recovery from that surgery.

    Also, based in Australia so our recommendations may differ from yours, but here we get aspirin as a recommendation as standard for most mechanical valve replacements, along with many other people.

  • My parents kicked me out recently. Why do we miss people who've treated us badly?
  • Yep, missing people who hurt you sucks. I have had that experience, it sucked a lot and took years to get through, but now I don't miss them at all. Honestly losing them was a great thing for me in the long run and it was a good opportunity to learn who I was and what I could do. I left at 17, never finished high school, but went on to have a great relationship with my now spouse, we worked together to raise her younger brothers from 12 through to 18, we have a cat who is an asshole that I love dearly, and we have moved more than a thousand kms away from my toxic trash family. I am happy now, you can be happy, this is just a shitty, bumpy start and it will be confusing, but the emotional systems you have will recalibrate and you will not miss them the same way you do now. Honestly I just regret for them that they couldn't see how silly they were being and how much they hurt myself and my siblings.

  • Lutris/Wine: Odd video pause every four seconds
  • You may be having a disk seek issue. Are you on a spinning disk? If so, sometimes running something a couple of times will have some cached or at least have the heads in the right spot to read the needed data. If that is the issue upgrading to an SSD would probably solve the issue at the root. A possible test would be using a RAM disk if you can be bothered testing it, you have sufficient RAM that it may be viable depending on the game.

    That all said, for next steps I would personally consider if maybe an older version of WINE would work. Could you try installing another older version of both the vanilla and GE versions? Also, did you update your nVidia drivers recently? Maybe roll back if your system will work with that, I can do it easily in EndeavourOS but Mint is not something I am recently acquainted with, it may be a real pain or may tank your driver install to try and roll back. Also testing installing a browser in WINE and loading a video that way may help troubleshoot, or VLC through WINE and native to compare. Ultimately you want to try and find the difference between the failed states and the working states, so if you come back bring a log from a working run and a failed run.

  • Warfarin dose in this study seems very similar in outcomes but does not meet non inferiority. Why?

    This study is talking about two groups, one with a target INR of 2.0-2.5 and the other with a target INR of 2.5-3.5. The higher dose is the current standard dose.

    The outcomes were extremely close group to group and it looks like the Confidence Interval was greater than 1.5%, so the study was not adequately powered to have confidence of non inferiority. Is that interpretation correct? Obviously the difference in the groups was not large, but it reads to me that they couldn't be sure it was close enough to not be worse with the lower dose, therefore they can't eliminate the possibility that low dose treatment is more dangerous than current dose? If so, would they do another study or would that basically amount to p-hacking? Further thoughts are appreciated.

    3
    Period tracking app refuses to disclose data to American authorities
  • I think piecemeal is a good way to go. Switch from MS Office to LibreOffice, from iOS to android, from Photoshop to Krita, then go to dual booting Linux (probably Mint or similar) with Windows, learn more using both, find what things you reboot to Windows for, find solutions for those using Wine and alternative software, get used to solving problems in Linux land and learn the tools. Once you are comfortable with a mix of both get rid of what you can, use Windows less and less, try CalyxOS or Graphene for your phone if possible, keep making steps. Each step makes progress, and imperfect solutions are a better starting point for finding better solutions.

    That said, for the earliest steps a virtual machine is an amazing tool, as is an old laptop. You can learn to solve problems on virtual or real hardware without making your life harder then inch closer to freedom. I've been using Linux since 2006 and honestly it has been a constant learning process. The first year was mostly VM learning, then an accidental install on my external HDD taught me about hubris and data protection. Since then I have kept moving towards more open hardware and software one step at a time. Getting started is the key, nothing teaches as well as trying.

  • Period tracking app refuses to disclose data to American authorities
  • What OS do you use? Windows, Mac, Linux? And same for your phone? Android? If so, you should be able to get it set up on your desktop and phone.

    First, get it installed on your desktop. For windows and mac go to the Syncthing download page and grab the installer. On Linux you will find install instructing below, but basically use your package manager to install syncthing.

    Once it is installed you can start it up and it will open a GUI, most likely through your web browser (probably 127.0.0.1:8384 or similar). From here you will have your Syncthing interface for your computer set up, so on to the phone.

    On your phone install syncthing from whichever store you use, fdroid is my favourite. Once installed open it and you should have an option to add another device. You can use this to scan the QR code on your computer Syncthing interface.

  • Period tracking app refuses to disclose data to American authorities
  • Good idea is to use something like Syncthing to copy data between your phone and another device like a laptop or another phone. This depends on the app, for Drip you have to manually export the data yourself on a regular basis.

    Another useful idea is if you have an old phone lying around get it connected via Syncthing and back up everything to it. If your current phone dies or is lost you can switch back immediately, a hot backup. If you have root on your device you can use NeoBackup to schedule backups of the data into a folder Syncthing can access and send to backup locations, say a home computer or spare device.

  • To Everyone Who Voted for Trump
  • I haven't seen that myself but I have a number of instances blocked, so from a filtering perspective I assume nothing and accept I don't know.

    That said, regardless of platform the Nazis are out in force and will be for as long as it takes for it to be shameful again.

    Make Nazis the Bad Guys Again. Ffs, it isn't a hard question, Nazi = bad, we already knew this, we should not have to relearn this.

  • EV with ‘unlimited’ range tested, car battery’s energy increases as it travels more
  • This is absolute bunkum. It is a zero point energy device, a similar idea to a cold fusion reactor, and absolutely not real. The fact that this got published on MSN.com is an indictment of their editorial process, suggesting that they would also post "bat boy" and alien abduction stories.

  • What's a really great audio book you are listening to at the moment?
  • Steven Gould - Jumper

    Barring the character names and teleportation it shares little with the movie, though I think the movie wasn't all that bad tbh. The idea is a kid with an abusive single dad discovers he can teleport. He acts like a kid would, making lots of mistakes, and figures out his teleportation and how to live.

    The novel is a little old so characters are a little shallow and stereotypical but honestly way less than expected. I have listened to the novels before but come back every so often for a repeat.

  • What's a really great audio book you are listening to at the moment?
  • Yeah, the children are only for setting some of the scene, but they come back for a few short (like less than 5 minute) scenes. The easiest solution is double speed, it is extremely listenable with that small change and well worth the effort.

  • What's a really great audio book you are listening to at the moment?
  • Every time I relisten I a gutted around that point. Very impactful character development, such a painful loss to move through and explored so well. Honestly one of the most emotionally impactful novels I have read possibly because of how much I enjoyed the differing Bobs bouncing of each other and finding equilibrium. I've listened to the first 4 around 5 times through and book 5 twice now, honestly on the edge of my seat for book 6.

  • (SOLVED!) Please help with Running Baldur's Gate 3 on linux (Debian)
  • It is possible, can you confirm the filesystem your steam install is on? The T7 mount looks like an automatic user mount, is it a standard ext4 or btrfs partition? Also, why is it mounting there, not in a fixed location denoted in your /etc/fstab file? If it is just automatic mounting there are some possible issues that could come from that, it may be worth testing another windows game through proton installed in the same steam library folder.

    That all said, you definitely need to have proton installed. If you go to your steam library you should be able to search for proton there. I would recommend installing the current version, the experimental, and if it is there proton-ge. I haven't used Debian for a while so I don't know what is in your repos but searching for proton-ge there may also have results.

    Once you definitely have the latest and experimental versions try switching version, testing with protontricks. It should show up both versions and allow you to switch between them without problems. You may also need to define your proton prefix as an environmental variable, something like PROTONPREFIX=/path/to/your/T7/proton/prefix/

    If you can't get that going consider jumping on to a matrix channel for more second by second help, tonnes of people are happy to help you get wine/proton working correctly.

  • (SOLVED!) Please help with Running Baldur's Gate 3 on linux (Debian)
  • When you need a component such as the .NET framework you can install it in Wine/Proton using the Windows installers. The .exe you are being recommended should be able to run, but the other way around it is to use something like protontricks, a proton version of winetricks (technically it uses winetricks and is more of a set of integrations and a GUI, but yeah). Using protontricks you can install the .NET framework, the C++ runtimes, dxvk, and other tools. I would recommend learning a little about how to use protontricks and maybe look for a few specific tutorials for using it with specific games to get a feel for it.

  • The Wild Robot spoiler-free review
  • This is a great review. It tells me if there is a deal breaker, say a wildly obvious plot hole, as well as giving some of the impact and experience of the movie. The conclusion is a simple number out of ten, along with a verbal recommendation. 9/10, good review, worth a quick read.

  • Can you "grow" a human from 2 sets of same sex parent DNA?
  • There are three genomes that go into an embryo. One from the chromosomes of the large gamete, the egg, one from the chromosomes of the small gamete, the sperm, and one from the mitochondria, in humans from the egg as well. If you had two XX donors you could make XX kids. If you had two XY donors you could make XX, XY, and YY variants. The only viable ones would be XY and XX, YY would not reach gestation.

    That said, if you took the DNA from gametes from each, removed the nucleus and mitochondria of an egg, added the total gametic DNA from both to the cell, added a mitochondria from either donor, then it should, in theory, be a viable egg like in IVF. This is actually a strategy for dealing with a mitochondrial disease by donating mitochondrial DNA from another source rather than those impacted by the disease. The problem would be there are many ways for this to go wrong and be left with an unviable embryo, so it would likely take many many eggs and many many donated cells to get a single viable egg with the donated DNA. That said, it could technically work.

  • Bream meame

    So we're doing breams now?

    1

    Very low ketones after 2 months strict carnivore

    My partner (36 XX) is two months in to very strict carnivore, eating exclusively beef mince and grass fed butter. Total intake is 1-1.5kg been mince and 200-300g butter per day. The only beverage is water or Powerade (sugar free, acesulfame K, sucralose).

    Her ketones on a blood meter are consistently low, maxing out at 0.2 mmol/L today. She feels tired, fatigued, and has burning in muscles suggesting lactic acid being elevated.

    Just looking to see if anyone has seen something similar and if so what the solution was? Thanks

    8