No shit, nicotine like all other stimulants like vyvanse or Adderall or even coffee are all vasoconstrictors. So are 5-HT2A psychs like shrooms and LSD.
The findings in nic free juice are interesting though. I'd also like it if there was a study on nicotine salts specifically.
Older vapes used freebase nicotine, quite unpleasant in high doses, like 6mg/10ml, so we vaped a lot of juice with a smaller nicotine concentration.
On the other hand nic salts are a very different ballgame, elfbars have like 24mg/10ml strength and you feel no throat hit at all. It feels "unnatural" and vibes tell me to worry.
During three separate sessions, participants had two MRI scans each—one before and one after smoking or vaping episodes, which included tobacco cigarettes, e-cigarette aerosol with nicotine, and e-cigarette aerosol without nicotine.
Should be noted these results are present for cigarettes too.
So far the "negatives" for vaping is almost always something that already happens for smoking, but it's overshadowed by the fact that smoking via combustible products is carcinogenic, and "gives you cancer".
Anything that can be said negatively about vaping, is generally 100x worse with smoking, plus, smoking gives you cancer, so......
Long story short: vaping is less bad than smoking.
This does not and should not imply that it is good for you. It is simply less harmful.
The uniquely bad part about vapes has to do with the waste. Cigarette butts aren't good for the environment or anything but disposable electronics are particularly bad
One of the only situations where an entire industry self-regulated out diacetyl(sp?) due to common sense.
I personally couldn't believe it when I saw it happen. Everyone just kinda agreed and started pulling all of it. Extract companies started labeling shit... I was flabbergasted.